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In Vitro Studies

The iontophoretic in vitro delivery of several anti-fungal drugs has been studied using porcine nails in the company's Onychomycosis screening assay. This screening system has enabled Power Paper to develop novel formulations optimized for delivery into the nail. The company further verified that the drug retains its antifungal activity after iontophoretic delivery through the nail. The graph below shows delivery to the nail bed of over 120 µg/cm2 of one of the company's lead anti-fungal drugs, using the Power Paper active patch device and novel drug formulation.

 

 

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